Kyzatrex™ is taken orally, which is more convenient than injections or gels. It causes only small increases in blood pressure, mainly in those on blood pressure meds, and has minimal impact on heart rate. It doesn't significantly affect red blood cell levels, reducing the risk of polycythemia compared to injections. Kyzatrex™ also has a stable cardiovascular profile, making it a good option for those needing testosterone replacement.
Further Reading:
- White, W. B., Bernstein, J. S., Rittmaster, R., & Dhingra, O. (2021). Effects of the oral testosterone undecanoate KyzatrexTM on ambulatory blood pressure in hypogonadal men. The Journal of Clinical Hypertension, 23(7), 1420–1430. https://doi.org/10.1111/jch.14297
- A. Michael Lincoff, Bhasin, S., Panagiotis Flevaris, Mitchell, L. M., Shehzad Basaria, Boden, W. E., Cunningham, G. R., Granger, C. B., Khera, M., Thompson, I. M., Wang, Q., Wolski, K., Davey, D., Vidyasagar Kalahasti, Khan, N., Miller, M. G., Snabes, M. C., Chan, A., Dubcenco, E., & Li, X. (2023). Cardiovascular Safety of Testosterone-Replacement Therapy. https://doi.org/10.1056/nejmoa2215025
- Kovac, J. R., Rajanahally, S., Smith, R. P., Coward, R. M., Lamb, D. J., & Lipshultz, L. I. (2014). Patient Satisfaction with Testosterone Replacement Therapies: The Reasons Behind the Choices. The Journal of Sexual Medicine, 11(2), 553–562. https://doi.org/10.1111/jsm.12369