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What is an undecanoate?

Updated

An undecanoate is a type of chemical compound used to make testosterone last longer in the body. Specifically, testosterone undecanoate is testosterone attached to an undecanoate ester, which slows down its release into the bloodstream. This means it provides a steady and prolonged effect, making it useful for testosterone replacement therapy. The undecanoate helps testosterone be absorbed through the lymphatic system when taken orally, avoiding rapid breakdown in the liver and maintaining stable testosterone levels.

Further Reading:

  1. Edelstein, D., & Basaria, S. (2010). Testosterone undecanoate in the treatment of male hypogonadism. Expert Opinion on Pharmacotherapy, 11(12), 2095–2106. https://doi.org/10.1517/14656566.2010.505920
  2. Testosterone undecanoate--oral therapy for male hypogonadism. (1985). Drug and therapeutics bulletin, 23(2), 7–8. 
  3. Kapoor, A. (2016). What’s new in testosterone deficiency research? Canadian Urological Association Journal, 10(5-6S), 130. https://doi.org/10.5489/cuaj.3915