Suppression of Natural Testosterone Production
- Kyzatrex, like other forms of testosterone replacement therapy (TRT), can suppress natural testosterone production. When the body receives testosterone from an external source, it tends to reduce or stop its own natural production. This effect is called negative feedback on the hypothalamic-pituitary-gonadal axis, which plays a central role in regulating testosterone levels.
- When exogenous testosterone is introduced, it can cause the body to reduce or stop its own natural testosterone production. This mechanism helps maintain hormone balance, but it results in a decrease in the body's internal production when external testosterone is provided. This suppression is common to all forms of TRT, not just Kyzatrex. The body senses sufficient testosterone levels due to external supplementation and subsequently reduces its natural output. This is a crucial aspect of TRT to keep in mind.
Recovery After Stopping Kyzatrex
- If you stop taking Kyzatrex after extended use, it may take some time for your body to resume normal testosterone production. The body's natural production mechanisms need time to reactivate, which may have been dormant during TRT.
- Recovery time can vary significantly. Some individuals recover quickly, while others take longer depending on health, age, and duration of TRT use.
Individual Variability in Suppression - The extent and duration of suppression can differ between individuals. Factors such as health, age, overall hormone levels, and the length of TRT usage all influence how quickly natural production resumes.
- This variability highlights the importance of close medical supervision during and after TRT treatment.
Stable Hormone Levels with Kyzatrex
- Kyzatrex is designed to mimic the body's natural testosterone production rhythm, providing more stable hormone levels compared to some other TRT forms.
- By following the body’s natural cycle, Kyzatrex aims to minimize fluctuations that could lead to side effects or inconsistent results, offering a more consistent and physiological approach to hormone replacement.
Clinical Effectiveness
- In clinical studies, Kyzatrex demonstrated effectiveness in normalizing testosterone levels in hypogonadal men, with up to 96% of patients achieving normal levels after 90 days of treatment. This high success rate shows that Kyzatrex is effective in helping men with testosterone deficiency.
Effects on Hormone Levels
- Kyzatrex affects hormone levels beyond total testosterone. It increases free testosterone levels and decreases sex hormone-binding globulin (SHBG) levels, ensuring more of the hormone is available for the body to use.
- This approach supports improved energy, mood, and overall health.
Note: If you have further questions about Kyzatrex or its effects on natural testosterone production, reach out to our support team for more personalized advice.
Further Reading:
- Marius Pharmaceuticals receives FDA approval of KyzatrexTM, an oral testosterone replacement therapy. BioSpace. (2022, August 2). https://www.biospace.com/marius-pharmaceuticals-receives-fda-approval-of-kyzatrex-an-oral-testosterone-replacement-therapy
- WebMD. (2024). Kyzatrex oral: Uses, side effects, interactions, pictures, warnings & dosing. WebMD. https://www.webmd.com/drugs/2/drug-185167/kyzatrex-oral/details
- Kyzatrex side effects: Common, severe, long term. Drugs.com. (2023, September). https://www.drugs.com/sfx/kyzatrex-side-effects.html
- White, W. B., Bernstein, J. S., Rittmaster, R., & Dhingra, O. (2021). Effects of the oral testosterone undecanoate KyzatrexTM on ambulatory blood pressure in hypogonadal men. The Journal of Clinical Hypertension, 23(7), 1420–1430. https://doi.org/10.1111/jch.14297
- Why Kyzatrex | Safe to Use, Easy to Take, and Up to 96% Effective. (2024). Kyzatrex. Retrieved May 17, 2024, from https://www.kyzatrex.com/why-kyzatrex/